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metronidazole will boost the stage or effect of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.cenobamate will improve the amount or result of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Check Carefully. Consider a dose reduction of CYP2C19 substrates, as clinically acceptable, w